In this article, we tackle the epistemological and ethical issues related to the use of race concepts in the genomics of sport performance and sport-related concussion (SRC). In the first part of the article, we show how the concept of race is ubiquitous in scientific literature, besides the fact that ‘race’ as other analogous population descriptors like ‘ancestry’ and ‘continent’ carry ancestral genetic heterogeneity and therefore they cannot be used to infer any kind of genetic or physiological property. Then, we (...) investigate the question of whether genomics research focusing on racial categories and race-specific genes of sport performance and of risk of health outcomes due to repetitive head impacts (RHI) is justified from an epistemological point of view, arguing that it is not; we show that the evidence supporting the existence of genetic variants determining an elite athlete status or a predisposition to health outcomes after SRC is scarce, and the use of racial categories (e.g. African or Black, Caucasian or White, Asian, etc.) as proxies for genetic variants associated with an elite athlete status/a predisposition to health outcomes after SRC is ill-conceived. In the second part of the article, we analyze the main ethical issues concerning the reification of race concepts in sport genomics, also considering the more general issue of the ethical and social impact of the use of a genetic framework in the explanation of individual differences in sport performance and SRC. (shrink)

The aim of this article is to explain why knot diagrams are an effective notation in topology. Their cognitive features and epistemic roles will be assessed. First, it will be argued that different interpretations of a figure give rise to different diagrams and as a consequence various levels of representation for knots will be identified. Second, it will be shown that knot diagrams are dynamic by pointing at the moves which are commonly applied to them. For this reason, experts must (...) develop a specific form of enhanced manipulative imagination, in order to draw inferences from knot diagrams by performing epistemic actions. Moreover, it will be argued that knot diagrams not only can promote discovery, but also provide evidence. This case study is an experimentation ground to evaluate the role of space and action in making inferences by reasoning diagrammatically. (shrink)

1. Transmodernity, in the words of Irena Ateljevic, is “an umbrella term that connotes the emerging socio-cultural, economic, political and philosophical shift” which we are experiencing in the era...

Background The 2020-2021 coronavirus (Covid-19) pandemic is just the latest epidemic event that requires us to rethink and change our understanding of health. Health should no longer be conceived only in relation to human beings, but in unitary terms, as a dimension that connects humans, animals, plants, and the environment (holistic view, One Health). In general, alterations occurring in this articulated chain of life trigger a domino effect. Methodology In this paper, we review the One Health paradigm in the light (...) of the Covid-19 pandemic and distinguish two approaches within it that might be dubbed the Prudent one and the Radical one. Each approach is structured in three levels – epistemological, medical, and ethical. Results In this way, we show how we humans can better address the pandemic today and how, in the future, we can treat the whole living system better, by renouncing our anthropocentric perspective on health. Conclusion We hold that the Prudent approach can be very helpful, and we discuss the medical and ethical issues related to it. We also consider the Radical view and the epistemological turn it requires compared to the Prudent one. (shrink)

In this paper we develop the notion of formal precover in a topos by defining a relation between elements and sets in a local set theory. We show that such relations are equivalent to modalities and to universal closure operators. Finally we prove that these relations are well characterized by a convenient restriction to a particular set.

En el trabajo se propone difundir la teoría y los enfoques referidos a la ciencia de la sostenibilidad, con especial énfasis en el contexto académico cubano, al relacionar su emergencia a las urgencias que surgen en los vínculos entre la ciencia, la naturaleza y la sociedad, así como mostrar las articulaciones de la Ciencia de la Sostenibilidad con la política científica, la educación universitaria y la salud pública. In this paper, the theory and the approaches of the science of sustainability (...) is promoted. Special emphasis is put on the academic Cuban context, when relating its emergence to the urgencies that appear within the links among science, nature and society. The interconnections of the science of sustainability with the scientific policy, the university education and the public health is shown as well as. (shrink)

Investigar a los buenos profesores es complejo porque se corre el riesgo de generalizar trivializando sus características, por lo mismo, es fundamental no caer en la tentación de pensar que son ideales, puesto que son seres humanos que viven su existencia al igual que cada uno de nosotros, sólo que con compromiso y amor por lo que hacen. Gracias a las historias de vida pudimos entender el proceso de la profesionalización docente, develar sus principales complejidades y señalar tendencias válidas para (...) cualquier profesor que pueden ajustarse con flexibilidad a esos patrones. La construcción analítica nos aportó luces para entender y explicar qué es lo que hace a un profesor un Buen Profesor. Esto es, la valoración del sentido común, la improvisación, la conciencia del cambio, la reflexión y la acción pedagógica. Sus características pueden ser intencionalmente promovidas en las distintas etapas de formación profesional porque tienen la cualidad de generar entusiasmo, contagio con un compromiso pedagógico, social y político por el trabajo bien hecho. (shrink)

Drug resistant epilepsy is one of the most complex, multifactorial and polygenic neurological syndrome. Besides its dynamicity and variability, it still provides us with a model to study brain-behavior relationship, giving cues on the anatomy and functional representation of brain function. Given that onset zone of focal epileptic seizures often affects different anatomical areas, cortical but limited to one hemisphere, this condition also let us study the functional differences of the left and right cerebral hemispheres. One lateralized function in the (...) human brain is emotional prosody, and it can be a useful ictal sign offering hints on the location of the epileptogenic zone. Besides its importance for effective communication, prosody is not considered an eloquent domain, making resective surgery on its neural correlates feasible. We performed an Electronic databases search (Medline and PsychINFO) from inception to July 2017 for studies about prosody in epilepsy. The search terms included “epilepsy,” “seizure,” “emotional prosody,” and “vocal affect.” This review focus on emotional prosody processing in epilepsy as it can give hints regarding plastic functional changes following seizures (preoperatively), resection (post operatively), and also as an ictal sign enabling the assessment of dynamic brain networks. Moreover, it is argued that such reorganization can help to preserve the expression and reception of emotional prosody as a central skill to develop appropriate social interactions. (shrink)

This work presents the case of the Yanomami indigenous people from Brazil that were the object of US ethnography initiated in the 1960s. The research brought harmful repercussions to the life of the Indigenous people of Brazil for several decades, and it took more than 40 years until the beginning of a process of reparation involving the Brazilian government and American universities. Objective: to discuss the meaning of the return of Yanomami blood samples, as well as contributions from the epistemologies (...) of traditional Indigenous knowledge to the debate about research ethics and the structuring of means for the social control of researchers and the protection of participants in scientific studies, having as an example the Yanomami indigenous people from Brazil, subjected to noxious ethnography in the 1960s and the 1970s. This work used data reports recorded in secondary sources. In this article we argue that Bioethics needs to further diversify its epistemological foundations and to consider epistemologies and cosmologies beyond the frontiers of Western science, as the case of the abusive research involving the Yanomami indigenous people in Brazil reveals. We argue that traditional knowledge, such as those of indigenous and quilombolas, with their epistemologies and cosmologies, are fundamental for the election of less colonized and more efficient principles of research ethics, regarding the protection of the participants' rights in scientific studies. Traditional indigenous populations can teach us a great deal about doing research. (shrink)

OBJECTIVES: This reliability generalization study aimed to estimate the mean and variance of the interrater reliability coefficients (ryy) of supervisory ratings of overall, task, contextual, and positive job performance. The moderating effect of the appraisal purpose and the scale type was examined. It was hypothesized that the ratings collected for research purposes and multi-item scales have higher ryy. It was also examined whether ryy was similar for the four performance dimensions. METHOD: A database consisting of 224 independent samples was created (...) and hierarchical sub-grouping meta-analyses were conducted. RESULTS: The appraisal purpose was a moderator of ryy for the four performance dimensions. Scale type was a moderator of ryy for overall and task performance collected for research purposes. The findings also suggest that supervisors seem to have less difficulty evaluating overall job performance than task, contextual, and positive performance. The best estimates of the observed ryy for overall job performance are.61 for research-collected ratings and.45 for administrative-collected ratings. MAIN CONCLUSIONS: (1) Appraisal purpose moderates ryy and researchers and practitioners should be aware of its effects before collecting ratings or using empirically-derived interrater reliability distributions, (2) Scale type seems to moderate ryy in the case of the ratings collected for research purposes, only, (3) overall job performance is more reliably rated than task, contextual, and positive performance. Implications for research and practice are discussed. (shrink)

After a brief introduction about the problem of leopardian sources, I wish to introduce here a description of the diffusion of Addison’s theories about the Imagination in Italy at the time of Leopardi, trying to highlight their influence on his thinking and his philosophy. The third chapter is dedicated to the analysis of an important excerpt of the Zibaldone where Leopardi quotes Addison and his Catone to introduce an interesting reflection about the pleasure of beauty and the role of imagination, (...) almost as a way to face Addison issues.This excerpt represents an occasion to compare the theories of Addison and Leopardi about Aesthetics and also the similarities and the differences between them. The last part of the paper is dedicated to the results of the analysis and the conclusions. (shrink)

The ?West? is inclined to blame Asian countries, especially China, for its disrespect of human rights without looking at it's own record of human rights violations! This makes a fair dialogue very difficult till improbable. Social work on the international level can't avoid this dialogue if it wants to live up to its internationally consensual documents which all refer to human rights. The thesis of this article is, that it will only succeed, if it clarifies some philosophical and ethical premisses (...) of so-called ?western? and ?oriental/asian? thinking. Thus, the article tries to show that concepts of ?holism?, ?atomism/individualism? and ?systemic thinking? might be helpful for a ?rejonder? and discussion platform for the analysis of different modes of thinking about ethical issues. A systemic approach tries to avoid the problematic and combine the positive aspects of individualistic and holistic approaches. An example for this combination is the ?Asian Human Rights Charter: A People's Charter? of 1998 which doesn't divide the freedom and participatory versus social rights, a divide which is typical ? and problematic ? for the western version. (shrink)

Da un lato al bene, ovvero a ciò che ci compie, non possiamo non tendere sempre, dall’altro il bene stesso esercita un’attrazione e una pretesa sulla nostra vita.

Sílvia Coll-Vinent, licenciada en Filología Catalana por la Universidad Autónoma de Barcelona y doctora por la Universidad de Oxford, es profesora de la Facultad de Filosofía de la Universidad Ramon Llull (Barcelona).

The activity of Wnt and Notch signalling is central to many cell fate decisions during development and to the maintenance and differentiation of stem cell populations in homeostasis. While classical views refer to these pathways as independent signal transduction devices that co‐operate in different systems, recent work has revealed intricate connections between their components. These observations suggest that rather than operating as two separate pathways, elements of Wnt and Notch signalling configure an integrated molecular device whose main function is to (...) regulate transitions between cell states in development and homeostasis. Here, we propose a general framework for the structure and function of the interactions between these signalling systems that is focused on the notion of ‘transition states’, i.e. intermediates that arise during cell fate decision processes. These intermediates act as checkpoints in cell fate decision processes and are characterised by the mixed molecular identities of the states involved in these processes.Editor's suggested further reading in BioEssays: Notch: Implications of endogenous inhibitors for therapy Abstract. (shrink)

What are the relevant values to the appraisal of research programs? This question remains hotly debated, as philosophers have recently proposed many lists of values potentially relevant to scientific appraisal. Surprisingly, despite being mentioned in many lists, little attention has been paid to fruitfulness. It is unclear how fruitfulness should be explicated, and whether it has any substantial role in scientific appraisal. In this paper, I argue we should explicate fruitfulness as the capacity to develop of research programs. Moreover, I (...) provide a novel strategy to assess and compare the fruitfulness of programs focused on their research questions and heuristics. To illustrate how this strategy would work, I will discuss a case study, namely the adaptationist program in evolutionary psychology. (shrink)

In the years of the post-Darwinian debate, many American naturalists invoked the name of Lamarck to signal their belief in a purposive and anti-Darwinian view of evolution. Yet Weismann’s theory of germ-plasm continuity undermined the shared tenet of the neo-Lamarckian theories as well as the idea of the interchangeability between biological and social heredity. Edward Drinker Cope, the leader of the so-called “American School,” defended his neo-Lamarckian philosophy against every attempt to redefine the relationship between behavior, development, and heredity beyond (...) the epigenetic model of inheritance. This paper explores Cope’s late-career defense of neo-Lamarckism. Particular attention is dedicated to the debate he had with James Mark Baldwin before the publication of Baldwin’s own “A New Factor in Evolution”. I argue that Cope’s criticism was partly due to the fact that Baldwin’s theory of social heredity threatened Cope’s biologistic stance, as well as his attempt to preserve design in nature. This theoretical attitude had a remarkable impact on Baldwin’s arguments for the theory of organic selection. (shrink)

This essay argues that despite of the feminist critique of Merleau-Ponty his phenomenology can be positively appropriated to the theory of sexual difference. It focuses on three issues: the first one is closely linked to the Phenomenology of Perception and introduces a concept of "difference as differentiation". The second one is concerned with the intersubjective dimension of sexuality and will be called a "sexual syncretism". Finally, I’m referring to Merleau-Ponty's notion of "chiasm" in his late work The Visible and the (...) Invisible in order to apply it to the theory of sexual difference. At this point, the difference between sexual beings will be conceptualized as "chiasmatic intertwining". In doing so, I hope to show that Merleau-Ponty's phenomenology is a helpful resource for philosophical research that is mainly concerned with the questions of sexuality and sexual difference. (shrink)

How does personality influence the relationship between appraisals and emotions? Recent research suggests individual differences in appraisal structures: people may differ in an emotion's appraisal pattern. We explored individual differences in interest's appraisal structure, assessed as the within-person covariance of appraisals with interest. People viewed images of abstract visual art and provided ratings of interest and of interest's appraisals (novelty–complexity and coping potential) for each picture. A multilevel mixture model found two between-person classes that reflected distinct within-person appraisal styles. For (...) people in the larger class (68%), the novelty–complexity appraisal had a stronger effect on interest; for people in the smaller class (32%), the coping potential appraisal had a stronger effect. People in the larger class were significantly higher in appetitive traits related to novelty seeking (e.g., sensation seeking, openness to experience, and trait curiosity), suggesting that the appraisal classes have substantive meaning. We conclude by discussing the value of within-person mixture models for the study of personality and appraisal. (shrink)

Modulating connectivity measures in EEG-based neurofeedback studies is assumed to be a promising therapeutic and training tool. However, little is known so far about its effects and trainability. In the present study, we investigated the effects of up- and down-regulating SMR coherence by means of neurofeedback training on EEG activity and memory functions. Twenty adults performed 10 neurofeedback training sessions in which half of them tried to increase EEG coherence between Cz and CPz in the SMR frequency range, while the (...) other half tried to down-regulate coherence. Up-regulation of SMR coherence led to between- and within-session changes in EEG coherence. SMR power increased across neurofeedback training sessions but not within training sessions. Cross-over training effects on baseline EEG measures were also observed in this group. Up-regulation of SMR coherence was also associated with improvements in memory functions when comparing pre- and post-test results. Participants were not able to down-regulate SMR coherence. This group did not show any changes in baseline EEG measures or memory functions comparing pre- and post-test. Our results provide insights in the trainability and effects of connectivity-based neurofeedback training and indications for its practical application. (shrink)

Abstract This paper is a close textual criticism of Theodosius Dobzhansky's Genetics and the Origin of Species. It argues that the book succeeds as interdisciplinary communication by promoting polysemy. The professional goals of two scientific communities are embedded in the text in such a way that each audience reads the call for co?operative action as implicit support for their own methods.

Scholars have often considered evolutionary social theories a product of Positivist scientism and the naturalization of ethics. Yet the theistic foundations of many evolutionary theories proposed between the nineteenth and the twentieth centuries bolstered the belief that following natural laws was morally desirable, if not vital, to guaranteeing social and moral progress. In the early twentieth century, American paleontologist and leading evolutionist Henry Fairfield Osborn represented one of the most authoritative advocates of this interpretation of natural normativity. Particularly during the (...) last years of his career, Osborn used theological arguments to reinforce his advocacy of evolutionary ethics and social control policies, which led him to challenge his “old master” Thomas Huxley regarding the separation between evolution and moral conduct. This article examines the development of Osborn’s evolutionary ethics, with particular regard to its bearing on the American debate on euthenics. I argue that theistic topics played a major rhetorical role in the attempt to justify normative conclusions drawn from ostensible laws of evolution. (shrink)

ABSTRACT Anthony Fauci, an infectious disease expert in the White House's coronavirus task force, is challenged to offer responsible public communication of science despite working under a habitual liar who has no tolerance for criticism or dissent. Fauci manages this rhetorical exigence by using strategic ambiguity, the topos of the honest broker, dissociation, and a narrative that constrains executive decision making.

This paper explores contract cheating from the perspectives of researchers at three post-secondary institutions in Alberta, Canada, describing their efforts to develop and advance awareness of, interventions against, and responses to contract cheating at their respective institutions. Contract cheating is when a third party produces or completes academic work for a student, and the student then presents the work as their own. The student might have personal connections to the third party, or the student might pay a fee and outsource (...) the academic work to the third party. All three institutions are experiencing an increase in the incidence of contract cheating, which is consistent with trends at colleges and universities across Canada and the world. Contract cheating is not a new phenomenon, but it is a growing one, due in part to students having access to thousands of online companies offering to help them with their academic work. This paper examines personal narratives from four researchers and identifies five key themes: types of contract cheating, students, awareness, evidence and policy implications, and educational development. (shrink)

ABSTRACT:This article aims to enhance understanding of employee anonymous online dissent (EAOD), a controversial phenomenon in contemporary digital environments. We conceptualise and scrutinise EAOD as a communicative and interactional process among four key actors: dissenting employees, online outlet administrators, audiences, and targeted organisations. This multi-actor, dialectical process encompasses actor-related tensions that may generate unethical consequences if single voices are not brought out and confronted. Appropriating a Habermasian ethical and discursive lens, we examine and disentangle three particular challenges emerging from the (...) EAOD process: lack of accountability and potential opportunism; equal participation and resolution of actor-related tensions; and organisational participation and internalisation of dissent. We show that EAOD can initiate plural dialogue that helps co-construct and balance different voices within an informal and noninstitutionalised context for interaction and public deliberation. We conclude our inquiry by offering reflections on practical implications and a research agenda for further investigation. (shrink)

Dieses Buch untersucht, was in den jeweiligen Theorieansätzen mit Bildhandeln‹ gemeint ist, indem eine Reihe von philosophischen und kunstwissenschaftlichen Ansätzen zum Verhältnis von Bild und Handlung vorgestellt und systematisiert werden. Vier paradigmatische Handlungstypen werden voneinander differenziert, die spezifische Verwendungsmöglichkeiten von Bildern umfassen. Die ersten zwei – Bildspiele‹ und Bildakte‹ – beruhen auf der sprachphilosophisch motivierten Prämisse, dass die Verwendung von Bildern der Struktur eines Sprachspieles oder eines Sprechaktes entspricht. Diese Prämisse bezieht sich auf Verwendungsweisen, durch die materiellen Gegenständen der Bildstatus (...) zugeschrieben wird. Demgegenüber werden zwei weitere Bildhandlungstypen vorgestellt, wonach Bilder nur dann verwendet werden können, wenn ihr Bildstatus bereits feststeht. Diese Bildhandlungstypen werden mit einem Vergleich von Bildern und Werkzeugen sowie der Kategorie Probehandlungen‹ thematisiert. (shrink)